With Knight Initiative support, Stanford researchers uncover a biochemical “off-ramp” in ketosis, rewriting our understanding of how ketosis influences metabolism.
A major goal in systems neuroscience is to discover how patterns of activity in neural circuits produce and regulate behavior. Using synthetic biology tools, this team aims to develop first-in-class genetically encoded voltage integrators (GEVIns) capable of sensing and responding to both activation and inhibition of neurons.
Controlling brain activity using chemicals and drugs is instrumental in neuroscience research, but current delivery methods for these compounds are imprecise. A proposed synthetic neural interface will allow for more controlled chemical and drug release by using ultrasound to precisely penetrate neural tissue.
Psychedelics profoundly alter human consciousness through activation of 5-HT2A receptor proteins in the brain. This team aims to develop a molecular probe to permanently illuminate 5-HT2A receptors without modifying their function or expression, allowing scientists to better study the effects of psychedelics on these receptors.
RNA sensors are a cutting edge tool in synthetic biology for probing complex molecular pathways and creating “smart” molecular circuits in cells. This team leverages state-of-the-art synthetic biology tools to understand how oligodendrocytes contribute to Alzheimer’s disease and other demyelinating disorders.
Groundbreaking research supported by the Knight Initiative for Brain Resilience at Stanford’s Wu Tsai Neurosciences Institute deepens our understanding of how the amino acid taurine may help reduce appetite and prevent obesity.
The Knight Initiative for Brain Resilience will host a "lab meeting style" seminar series to bring together awardees, affiliated professors, and students. Two speakers will discuss their brain resilience research, field experience, and answer questions about their work.
Why do our brains get worse at learning as we get older, and what can we do about it? Institute affiliate Carla Shatz discusses our brain's capacity for change on this podcast episode.
The Knight Initiative for Brain Resilience will host a "lab meeting style" seminar series to bring together awardees, affiliated professors, and students. Two speakers will discuss their brain resilience research, field experience, and answer questions about their work.
This week on From Our Neurons to Yours, we talk with memory expert Anthony Wagner about the nature of memory and how to improve it.