We’re unlocking the mysteries of lifelong brain resilience Through bold and innovative approaches, we’re decoding how brains stay healthy as we age and driving a future free from dementia. Our Research Featured articles Featured 01 / 04 Knight Initiative Fall 2025 Symposium Read More Under the Lights: What Surgery Reveals About Brain Resilience Read More Fueling the next phase of brain resilience: 2025 Catalyst Momentum Awards Read More Alzheimer's "resilience signature" predicts who will develop dementia—and how fast Read More Our collaborative approach to brain resilience research is unlike any institution in the world. Upcoming EventsJoin us to learn about exciting developments in brain resilience research. Knight Initiative Events / Seminar Brain Resilience Seminar: Jacob Simon and Joe Winer Sep 8 2025, 12:00 pm – 1:00 pm Knight Initiative Events / Seminar Brain Resilience Seminar: Kristy Zera and Carla Shatz Oct 6 2025, 12:00 pm – 1:00 pm Knight Initiative News View All News Fortune A scientific breakthrough researchers call ‘magic’ could transform treatment for a leading cause of death With support from a Wu Tsai Neuro grant, researchers have developed a potentially game-changing stroke treatment. Jul 9 2025 Newsday Brain health: It's 'biological age' might be able to predict your life span A new Stanford study used blood proteins to analyze the 'biological' age of brains and other organs compared to the person's actual age. Jul 9 2025 Brain aging Discovery science Molecules and cells The Mercury News Stanford researchers develop new tool to measure biological age The tool, built by a team led by Stanford's Tony Wyss-Coray, uses a single vial of blood to assess the 'biological age' of each organ. Jul 9 2025 Brain aging Discovery science Molecules and cells Featured Projects Innovation Awards | 2022 Mechanistic dissection and therapeutic capture of an exercise-inducible metabolite signaling pathway for brain resilience Lead Researcher(s) Jonathan Z. Long Team Members Thomas Montine, MD, PhD Steven Banik Research Keywords Brain resilience Discovery science Innovation Awards | 2022 Mutant microglia and resilience to Alzheimer’s disease Lead Researcher(s) Siddhartha Jaiswal Team Members Marius Wernig Jody Elizabeth Hooper Caleb Lareau Research Keywords Brain resilience Discovery science
Knight Initiative Events / Seminar Brain Resilience Seminar: Jacob Simon and Joe Winer Sep 8 2025, 12:00 pm – 1:00 pm
Knight Initiative Events / Seminar Brain Resilience Seminar: Kristy Zera and Carla Shatz Oct 6 2025, 12:00 pm – 1:00 pm
Fortune A scientific breakthrough researchers call ‘magic’ could transform treatment for a leading cause of death With support from a Wu Tsai Neuro grant, researchers have developed a potentially game-changing stroke treatment. Jul 9 2025
Newsday Brain health: It's 'biological age' might be able to predict your life span A new Stanford study used blood proteins to analyze the 'biological' age of brains and other organs compared to the person's actual age. Jul 9 2025 Brain aging Discovery science Molecules and cells
The Mercury News Stanford researchers develop new tool to measure biological age The tool, built by a team led by Stanford's Tony Wyss-Coray, uses a single vial of blood to assess the 'biological age' of each organ. Jul 9 2025 Brain aging Discovery science Molecules and cells
Innovation Awards | 2022 Mechanistic dissection and therapeutic capture of an exercise-inducible metabolite signaling pathway for brain resilience Lead Researcher(s) Jonathan Z. Long Team Members Thomas Montine, MD, PhD Steven Banik Research Keywords Brain resilience Discovery science
Innovation Awards | 2022 Mutant microglia and resilience to Alzheimer’s disease Lead Researcher(s) Siddhartha Jaiswal Team Members Marius Wernig Jody Elizabeth Hooper Caleb Lareau Research Keywords Brain resilience Discovery science