The discovery from an unusual team of computer scientists and pathologists overturns longstanding dogma – and could point the way toward new therapies for neurodegenerative disease
In a paradigm shift, Wu Tsai Neuro affiliate Bingwei Lu's lab has found a new role for a well-known protein linked to Alzheimer’s disease and other neurodegenerative disorders
Contrary to long-standing views, Knight Initiative-funded researchers found bone marrow-derived cells infiltrate the aging human brain, paving the way for brain-targeted cell therapies
The discovery from an unusual team of computer scientists and pathologists overturns longstanding dogma – and could point the way toward new therapies for neurodegenerative disease
Two immune cell types’ contact plays a major role in aging, and blocking a hormone’s influence on one of those types halted mice’s age-associated decline in multiple organs
Brief electrical pulses trigger a molecular “reboot and rebound” in sea squirts, pointing toward new strategies to mitigate age-related decline, according to research backed in part by the Knight Initiative for Brain Resilience.
In this research roundup, we look back on some of the ways Knight Initiative scientists have been pursuing ways to keep our minds sharp well into old age
Knight Initiative researchers created a new atlas of aging in the killifish tracks how organs change over time, revealing processes implicated in Alzheimer’s and Parkinson’s diseases
The Rosenkranz Aging and Rejuvenation Seed Grant Program announced eight innovative new research projects with additional support from the Knight Initiative for Brain Resilience
The snakes’ unique feeding behavior offers new clues about the gut-brain axis—and hints of a potential weight-loss drug with fewer side effects than GLP-1 drugs
Knight Initiative for Brain Resilience Steering Committee member Anne Brunet explores what aging really is, how lifestyle choices might influence longevity, and the promising frontiers of aging research
Aging causes changes in gut bacteria in mice, hampering communication between the intestines and the brain—but restoring this connection helped old mice form memories as well as young animals
Knight Initiative scientists tracked every moment of the life of the African turquoise killifish, showing that behavior alone can forecast whether an animal will live a long or short life
