Vadim Gladyshev
Professor of Medicine at Harvard Medical School, Director of the Center for Redox Medicine at Brigham and Women’s Hospital, Faculty member of the Broad Institute
Targeting Aging and Rejuvenation
Bio
Vadim Gladyshev is Professor of Medicine at Harvard Medical School, Director of the Center for Redox Medicine at Brigham and Women’s Hospital, and a faculty member of the Broad Institute. He earned his degrees at Moscow State University and trained at the National Institutes of Health. His laboratory studies aging, rejuvenation, and lifespan control using integrated experimental and computational approaches. He has authored more than 500 publications, is a recipient of the NIH Pioneer, Transformative, and Eureka Awards, and is an elected member of the U.S. National Academy of Sciences.
Abstract
Aging is viewed differently by researchers in the field, and its essence remains unclear. However, different manifestations of aging may now be quantified with integrative biomarkers trained for chronological age, mortality, functional decline, rate of age-related changes or accumulation of deleterious changes. Additionally, molecular signatures of processes that support longevity across and within species have been described. With all these tools, it is now possible to assess aging and longevity in a variety of experimental settings and test factors that target them. In particular, application of these tools suggests that it is possible to target biological age in both directions, and that biological systems may be rejuvenated.
About the Series
This collaborative seminar is a joint effort of the Knight Initiative for Brain Resilience and the Paul F. Glenn Center for Biology of Aging Research.
To support our researchers' participation in this open science "lab-meeting style" exchange of ideas, these seminars are not streamed/recorded and are only open to members of the Stanford community.