Comparison of amyloid PET acquired through standardized and unstandardized protocols

Karly A Cody, Andrzej Sokolowski, Lucah Medina Guerra, Philip S Insel, William J Jagust, Theresa M Harrison, Elizabeth C Mormino

INTRODUCTION: Amyloid positron emission tomography (PET) scans collected by Alzheimer''s Disease Research Centers (ADRCs) include site-specific "mixed protocols" and, since 2021, standardized protocols through the Standardized, Centralized AD/ADRD Neuroimaging initiative. We compared amyloid PET from cohorts using unstandardized versus standardized pre-processing protocols.'