Research Summary
This Knight Brain Resilience grant strategically builds on research funded by the Michael J. Fox Foundation (MJFF) to advance a new gene therapy for Parkinson’s disease. By leveraging MJFF’s investment, this grant expands the research to include advanced PET brain scans to assess dopamine function and inflammation, detailed analysis of how the therapy impacts brain and immune cells, and tracking of key proteins in blood and spinal fluid to measure its effectiveness. These efforts aim to refine the therapy, develop markers of success, and guide future clinical trials, accelerating progress toward more effective treatments for Parkinson’s.
