Pathologist Siddhartha Jaiswal discovers a surprising twist to our biology: age-related mutations that increase the risk of blood disease also protect against brain disease.
Interdisciplinary Postdocs and Brain Resilience Scholars will advance knowledge of brain health and aging.
The Phil and Penny Knight Initiative for Brain Resilience is proud to announce the recipients of its inaugural 2022 Innovation and Catalyst Grants.
With a new study published in Nature, Wu Tsai Neurosciences Institute researchers are helping to show that the cerebrospinal fluid that bathes our brains holds clues to healthy brain aging.
Katrin Andreasson discusses how immune cells can cause harmful brain inflammation and contribute to the development of neurodegenerative diseases like Alzheimer’s disease.
In this episode, chemist Jonathan Z. Long discusses his recent discovery of a new molecule produced when we exercise that appears to be linked to health benefits from regulating appetite to boosting learning and memory.
This team aims to be the first to study the cellular and molecular impact of traumatic brain injury by studying genetic material in human cerebrospinal fluid. This will help clinicians and researchers ID markers of brain resilience after injury, and ultimately improve treatment for severe TBI.
This team aims to better understand how Parkinson's disease attacks the brain's basic motor programs and to spawn novel therapies against the disease using gene-editing technology.
This project will explore whether amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) result from immune cells attacking altered neurons. The team aims to pioneer the use of engineered immune cells as therapies for neurodegenerative disorders.
Inflammation is a hallmark of brain aging, yet the source of inflammation in the old brain—and how to eliminate it—is unknown. This team aims to provide insight on how inflammation affects the aging brain that could potentially lead to the generation of new therapies to promote brain resilience.