Two new studies supported by the Knight Initiative highlight groundbreaking new early biomarkers for the diagnosis and treatment of neurodegenerative disease.
Disabling the notorious APOE4 gene might protect against the disease, according to research from Michael Greicius and team.
We are proud to welcome the 2024 Neurosciences Postdoctoral Scholars — ten young scientists pursuing novel, multi-disciplinary approaches to understanding the workings of the brain.
Sleep is critical for brain function in many animals, and chronic disruptions in sleep patterns are strongly linked to the emergence of neurodegenerative diseases like Alzheimer’s and Parkinson’s. When animals sleep, neural activity and brain metabolism change dramatically; however, we do not know what the molecular functions of sleep are in the brain, nor do we know how these processes are linked to brain health.
Neuroinflammation is common in several neurodegenerative diseases, with brain immune cells, specifically microglia, being a main driver of the inflammatory process. Understanding what triggers microglial activation and its pathways will lead to a better knowledge of inflammatory mechanisms involved in neurodegenerative disease pathology. Circular RNAs (circRNAs) have been studied extensively in the peripheral immune system due to their ability to induce innate immune responses.
Alzheimer’s disease (AD) is the sixth leading cause of death in the United States and there is a tremendous need for improved therapeutic strategies to treat this prevalent neurodegenerative disease. A devastating symptom of AD is progressive memory loss; this particular disease feature has proven difficult to treat. However, research has begun to unravel novel drivers of AD, including the important role the body’s immune system plays in promoting memory loss.
The Wu Tsai Neurosciences Institute at Stanford University is proud to announce the recipients of its fifth round of Seed Grants.
Working in the Gibson Lab, Brain Resilience Postdoc Scholar Daniela Rojo looks at how abnormal changes in gene activity impact the cells involved in producing myelin to the extent that it leads to neurodegeneration in the brain.
A new study demonstrating CRISPR gene editing in killifish opens the doors for ambitious research on the biological drivers of aging.
Interdisciplinary Postdocs and Brain Resilience Scholars will advance knowledge of brain health and aging.