Knight Initiative scientists tracked every moment of the life of the African turquoise killifish, showing that behavior alone can forecast whether an animal will live a long or short life
Neuroscience News
Featured News
Q&A: Probing electrical signals to understand Alzheimer’s disease
Brain Resilience Postdoctoral Scholar Annie Goettemoeller is studying how epilepsy-like activity might drive the spread of Alzheimer’s pathology in the brain
Researcher profiles
Engineered immune therapy could help fight brain aging
Neuroscientists studying inflammation and age-related brain decline engineered a protein that spurs the growth of new neurons in aging mice
Research news
Preventing Parkinson’s, a new Alzheimer’s drug, and more featured at tenth Knight Initiative Symposium
Researchers from around the world convened at Stanford to present their latest work on neurodegeneration and brain resilience
Knight Initiative news
Fixing the Aging Brain
The number one thing most people fear as they age is developing dementia. As the world’s population becomes increasingly older, this is a growing public health issue too.
Press coverage
Driver of neurodegenerative diseases revealed
In searching for how a gene mutation associated with the cell’s recycling center leads to a rare disease, Knight Initiative for Brain Resilience and Wu Tsai Neuro affiliate Monther Abu-Remaileh and team identified a missing link in neurodegenerative condi
Research news
Blood Cells Mutated in Old Age Protect Against Alzheimer’s Disease
Pathologist Siddhartha Jaiswal discovers a surprising twist to our biology: age-related mutations that increase the risk of blood disease also protect against brain disease.
Research news
Aging Mouse Brain Atlas Reveals White Matter Changes Most Over Time
A study in mice suggests that the most pronounced changes that occur over time are in the white matter—neurons that are integral to transmitting signals across the brain. The research also examined how two anti-aging treatments—caloric restriction and inf
Press coverage
Is the Brain’s White Matter an Unexpected Key to Aging and Memory?
Funded in part by the Knight Initiative, researchers at the Wyss-Coray Lab have discovered that age-related cognitive decline is most pronounced in the brain’s white matter in a new study.
Press coverage
Stanford Medicine-led research identifies gene ‘fingerprint’ for brain aging
A study in mice finds that white matter — the tissue that transmits messages around the brain — shows the greatest changes as the animals age.
Research news
To study aging, researchers give killifish the CRISPR treatment
A new study demonstrating CRISPR gene editing in killifish opens the doors for ambitious research on the biological drivers of aging.
Research news
Wu Tsai Neuro & Knight Initiative announce 2023 postdoctoral scholars
Interdisciplinary Postdocs and Brain Resilience Scholars will advance knowledge of brain health and aging.
Wu Tsai Neuro News
Knight Initiative news
Bold ideas to advance healthy brain aging win inaugural Knight Initiative grants
The Phil and Penny Knight Initiative for Brain Resilience is proud to announce the recipients of its inaugural 2022 Innovation and Catalyst Grants.
Knight Initiative news
Q&A: Evolution of octopus and squid brains could shed light on origins of intelligence
By studying the independent evolution of the cephalopod nervous system, researchers like Matt McCoy seek to look past the differences to see common features that could teach us fundamental truths about the evolution of intelligence itself.
Researcher profiles
Can we rejuvenate aging brains?
Tony Wyss-Coray and colleagues have turned up substances in blood that can accelerate or slow down the brain-aging clock. They've identified proteins on blood-vessel surfaces through which some of these molecules can act on the brain, despite the existenc
Research news
A rare mutation protects against Alzheimer's disease, Stanford-led research finds
An international collaboration led by Michael Greicius, MD, professor of neurology at Stanford Medicine, has found a rare mutation that protects against Alzheimer’s in individuals who are genetically predisposed to the disease.
Research news
Young cerebrospinal fluid may hold keys to healthy brain aging
With a new study published in Nature, Wu Tsai Neurosciences Institute researchers are helping to show that the cerebrospinal fluid that bathes our brains holds clues to healthy brain aging.
Research news
Q&A: How the aging immune system impacts brain health
Katrin Andreasson discusses how immune cells can cause harmful brain inflammation and contribute to the development of neurodegenerative diseases like Alzheimer’s disease.
Researcher profiles
Gift from Phil and Penny Knight launches scientific endeavor to combat neurodegeneration
A new initiative on brain resilience will study the causes of cognitive decline—what may be done to prevent, delay, or reverse the decline—and what goes right for those who keep their cognitive abilities intact.
Wu Tsai Neuro News
Knight Initiative news
Stanford neuroscientists take their Big Ideas on decision-making, neurotechnology and brain rejuvenation to the next level
The Wu Tsai Neurosciences Institute is elevating three research programs to become the flagship Big Ideas collaborations focusing on brain rejuvenation, neurotechnology and decision-making.
Wu Tsai Neuro News