Brain resilience

The genetic variant APOE4, carried by one-fifth of the world’s people, substantially boosts Alzheimer’s risk. But scientists have been puzzled about how to reverse that risk: punch up the gene variant’s potency, or smack it down? Now we know, thanks to research funded by the Knight Initiative for Brain Resilience.

Stanford's Office of Postdoctoral Affairs has named Hulya Torun one of this year's Postdoc Champions

A new study finds links between two popular models of the disease—and the results could change how researchers think about treatment.

Blood and cerebrospinal fluid markers tied to inflammation and metabolism sort some patients into subgroups, according to Knight Initiative researchers, a step toward predicting progression and tailoring care.

Knight Initiative-funded research ran the gamut from chemistry to public health, but one theme brought it all together: Studying what makes the brain resilient will help more people live better lives.

Four Stanford teams receive funding from the Knight Initiative for Brain Resilience to advance research on healthy brain aging and neurodegenerative diseases, including cellular resilience, a new theory of Parkinson’s Disease, and predicting individual aging trajectories.

Research supported by a Knight Initiative Catalyst Grant explores whether targeting pathways related to the brain’s “chill-out” system could restore youthful resilience and improve cognitive function.

Researchers at Stanford’s Knight Initiative for Brain Resilience merge spatial transcriptomics and AI to uncover how local cellular interactions drive brain aging and resilience