We’re unlocking the mysteries of lifelong brain resilience Through bold and innovative approaches, we’re decoding how brains stay healthy as we age and driving a future free from dementia. Our Research Featured articles Featured 01 / 06 Knight Initiative - Rosenkranz Aging Symposium Read More Gift advances research into brain resilience and aging Read More New ideas in aging and resilience research launched by Rosenkranz Foundation and Knight Initiative Read More Announcing the 2026 Neurosciences Postdoctoral Scholars Read More Watching a lifetime in motion reveals the architecture of aging Read More Q&A: Probing electrical signals to understand Alzheimer’s disease Read More Our collaborative approach to brain resilience research is unlike any institution in the world. Upcoming EventsJoin us to learn about exciting developments in brain resilience research. Seminar Shuke Xiao and Lun Wang Oct 5 2026, 12:00 pm – 1:00 pm Seminar Jan Karlseder Oct 26 2026, 12:00 pm – 1:00 pm Knight Initiative News View All News Stanford Medicine Emmanuel Mignot receives Lasker Award for discovering cause of narcolepsy The Wu Tsai Neuro affiliate found that narcolepsy stems from a deficiency of orexin in the brain, opening the door to new sleep therapies Sep 9 2026 Brain function Molecules and cells Discovery science Time Tony Wyss-Coray Is Measuring Biological Age One Organ at a Time The Knight Initiative for Brain Resilience director was featured in Time's 2026 list of Longevity Leaders Aug 24 2026 Brain aging Discovery science Molecules and cells Stanford Medicine Alzheimer’s-implicated protein tau scrambles nerve cells’ powerpacks In a paradigm shift, Wu Tsai Neuro affiliate Bingwei Lu's lab has found a new role for a well-known protein linked to Alzheimer’s disease and other neurodegenerative disorders Aug 13 2026 Brain aging Molecules and cells Discovery science Featured Projects Innovation Awards | 2022 Mechanistic dissection and therapeutic capture of an exercise-inducible metabolite signaling pathway for brain resilience Funded Researcher(s) Jonathan Z. Long Thomas Montine, MD, PhD Steven Banik Research Keywords Brain resilience Discovery science Innovation Awards | 2022 Mutant microglia and resilience to Alzheimer’s disease Funded Researcher(s) Siddhartha Jaiswal Marius Wernig Jody Elizabeth Hooper Caleb Lareau Research Keywords Brain resilience Discovery science
New ideas in aging and resilience research launched by Rosenkranz Foundation and Knight Initiative Read More
Stanford Medicine Emmanuel Mignot receives Lasker Award for discovering cause of narcolepsy The Wu Tsai Neuro affiliate found that narcolepsy stems from a deficiency of orexin in the brain, opening the door to new sleep therapies Sep 9 2026 Brain function Molecules and cells Discovery science
Time Tony Wyss-Coray Is Measuring Biological Age One Organ at a Time The Knight Initiative for Brain Resilience director was featured in Time's 2026 list of Longevity Leaders Aug 24 2026 Brain aging Discovery science Molecules and cells
Stanford Medicine Alzheimer’s-implicated protein tau scrambles nerve cells’ powerpacks In a paradigm shift, Wu Tsai Neuro affiliate Bingwei Lu's lab has found a new role for a well-known protein linked to Alzheimer’s disease and other neurodegenerative disorders Aug 13 2026 Brain aging Molecules and cells Discovery science
Innovation Awards | 2022 Mechanistic dissection and therapeutic capture of an exercise-inducible metabolite signaling pathway for brain resilience Funded Researcher(s) Jonathan Z. Long Thomas Montine, MD, PhD Steven Banik Research Keywords Brain resilience Discovery science
Innovation Awards | 2022 Mutant microglia and resilience to Alzheimer’s disease Funded Researcher(s) Siddhartha Jaiswal Marius Wernig Jody Elizabeth Hooper Caleb Lareau Research Keywords Brain resilience Discovery science