We’re unlocking the mysteries of lifelong brain resilience

Through bold and innovative approaches, we’re decoding how brains stay healthy as we age and driving a future free from dementia.

Featured 01 / 04

Knight Initiative Fall 2025 Symposium
Read More
Under the Lights: What Surgery Reveals About Brain Resilience
Read More
Fueling the next phase of brain resilience: 2025 Catalyst Momentum Awards
Read More
Alzheimer's "resilience signature" predicts who will develop dementia—and how fast
Read More

Our collaborative approach to brain resilience research is unlike any institution in the world.

Image

Brain Resilience Lab

Our research lab blends the innovation of a startup with the academic rigor and support of Stanford University, driving breakthroughs in healthy brain aging.
Image

Grants & Training Programs

Uniting scientists across disciplines to catalyze bold advances in the science of neurodegeneration, aging, and resilience.
Image

Resource Hub

Leveraging advanced tools in sequencing, spatial transcriptomics, and proteomics, we’re building a global library of brain aging datasets, empowering researchers to drive their own studies and advance collective knowledge on brain resilience.
Image

Brain Omics Central

Offering access to advanced omics technologies, including sequencing, spatial, and proteomics, alongside a growing brain tissue repository.

Upcoming Events
Join us to learn about exciting developments in brain resilience research.

Knight Initiative Events / Seminar Brain Resilience Seminar: Jacob Simon and Joe Winer

Sep 8 2025, 12:00 pm – 1:00 pm
Knight Initiative Events / Seminar Brain Resilience Seminar: Kristy Zera and Carla Shatz

Oct 6 2025, 12:00 pm – 1:00 pm

National Geographic Your brain could be 'older' than your age—and it's easier than ever to find out

Is your brain aging faster than your chronological age? New research shows it could raise your risk of death and dementia significantly—and offers promise for early intervention.
Jul 17 2025

Brain aging

Molecules and cells

Neurodegenerative disorders
Research news A new consortium opens unexpected windows into neurodegenerative disease

The Global Neurodegeneration Proteomics Consortium gathered a trove of data on potential signs of neurological disease—and researchers including Knight Initiative director Tony Wyss-Coray are already using it to make new discoveries.
Jul 16 2025
Knight Initiative news Knight Initiative symposium charts new frontiers in brain health

Knight Initiative-funded research ran the gamut from chemistry to public health, but one theme brought it all together: Studying what makes the brain resilient will help more people live better lives.
Jul 14 2025

Brain resilience

Brain aging

Clinical / translational research

Get the latest news from the Knight Initiative

Join our mailing list to receive updates about Knight Initiative news, events and opportunities delivered directly to your inbox.

Subscribe