Knight Initiative scientists tracked every moment of the life of the African turquoise killifish, showing that behavior alone can forecast whether an animal will live a long or short life
Neuroscience News
Featured News
Q&A: Probing electrical signals to understand Alzheimer’s disease
Brain Resilience Postdoctoral Scholar Annie Goettemoeller is studying how epilepsy-like activity might drive the spread of Alzheimer’s pathology in the brain
Researcher profiles
Engineered immune therapy could help fight brain aging
Neuroscientists studying inflammation and age-related brain decline engineered a protein that spurs the growth of new neurons in aging mice
Research news
Preventing Parkinson’s, a new Alzheimer’s drug, and more featured at tenth Knight Initiative Symposium
Researchers from around the world convened at Stanford to present their latest work on neurodegeneration and brain resilience
Knight Initiative news
Building bridges between Alzheimer’s theories
A new study finds links between two popular models of the disease—and the results could change how researchers think about treatment.
Research news
Rethinking how we learn to move in the world
Knight Initiative researchers are uncovering the fine points of how our brains learn to move. In the long run, their findings could help devise better treatments for Parkinson's disease.
Research news
"I Heard There Was a Secret Chord: Music as Medicine"
In this episode, we talk with neuroscientist, musician and author Daniel Levitin about his new book on the neuroscience of music and how it is being used to help heal disorders from Parkinson's to chronic pain
Podcast episodes
Study pinpoints key mechanism of brain aging
A study of killifish reveals how protein dysfunction develops in vertebrate brain cells, a key driver of aging – shedding light on cognitive decline and dise
Research news
Why promising dementia treatments work in mice but fail in people
Stanford researchers reviewed over 400 therapy evaluations and discovered a crucial mismatch: Mouse studies test disease prevention, while human trials test treatment of existing disease.
Research news
Alzheimer’s may stem from breakdown of “recycling centers” in aging cells
Knight Initiative researchers used a new lab model of aging human neurons to show that as cells age, lysosomes fall into disrepair and waste builds up—feeding a damaging cycle that could lead to Alzheimer’s.
Research news
Parkinson’s comes in many forms. New biomarkers may explain why
Blood and cerebrospinal fluid markers tied to inflammation and metabolism sort some patients into subgroups, according to Knight Initiative researchers, a step toward predicting progression and tailoring care.
Research news
Replacing brain immune cells in mice slows neurodegeneration
The technique, which used genetically healthy donor cells, prolonged life and function in mice with a disease similar to Tay-Sachs.
Research news
Koret Human Neurosciences Community Lab grants bring cutting-edge tools to Stanford scientists
The lab’s second crop of pilot awards will foster research in visual attention, the neurophysiology of exercise, and therapies for autism and mild cognitive impairment associated with aging.
Wu Tsai Neuro News
Alzheimer's Association honors Katrin Andreasson
Andreasson received the Inge Grundke-Iqbal Award for her work on restoring cognition in Alzheimer's. Karly Cody, a postdoctoral fellow in the lab of Knight Initiative researcher Elizabeth Mormino, was also honored.
Awards and honors
A new consortium opens unexpected windows into neurodegenerative disease
The Global Neurodegeneration Proteomics Consortium gathered a trove of data on potential signs of neurological disease—and researchers including Knight Initiative director Tony Wyss-Coray are already using it to make new discoveries.
Research news
Your brain could be 'older' than your age—and it's easier than ever to find out
Is your brain aging faster than your chronological age? New research shows it could raise your risk of death and dementia significantly—and offers promise for early intervention.
Press coverage
Knight Initiative symposium charts new frontiers in brain health
Knight Initiative-funded research ran the gamut from chemistry to public health, but one theme brought it all together: Studying what makes the brain resilient will help more people live better lives.
Knight Initiative news
Your brain reveals a lot about your age
Knight Initiative researchers developed a blood test that track the biological age of the brain and other organs.
Press coverage
Foundational research on brain development may help prevent degeneration
Stanford neurobiologist Carla Shatz, famous for discovering how neural connections develop early in life, is using that knowledge to work on the problem of how they can later deteriorate from Alzheimer’s disease.
Researcher profiles
Scientists Succeed in Reversing Parkinson’s Symptoms in Mice
The findings of two recent studies give hope that the disease could one day be reversed in humans—but experts warn that this complex disease will likely need multiple complementary treatments.
Press coverage