Publications

Research supported by Knight Initiative for Brain Resilience grants and fellowships is advancing our understanding of healthy brain aging and new approaches to combat neurodegenerative disease.

Acta Neuropath Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson's disease

Thomas J. Montine, Per Borghammer, Tony Wyss-Coray & Kathleen L. Poston, Jarod Rutledge, Benoit Lehallier, Pardis Zarifkar, Patricia Moran Losada, Marian Shahid-Besanti, Dan Western, Priyanka Gorijala, Sephira Ryman, Maya Yutsis, Gayle K. Deutsch, Elizabeth Mormino, Alexandra Trelle, Anthony D. Wagner, Geoffrey A. Kerchner, Lu Tian, Carlos Cruchaga, Victor W.
Mar 11 2024
Ann Clin Transl Neurol Multiple biomarkers improve diagnostic accuracy across Lewy body and Alzheimer's disease spectra

Kathleen L Poston, Melanie J PlastiKathleen Poston , Carla Abdelnour, Christina B Young, Edward N Wilson, Marian Shahid-Besanti, Jennifer Lamoureux, Katrin I Andreasson, Geoffrey A Kerchner, Thomas J Montine, Victor W Hen
Mar 4 2024
Nature Stress response silencing by an E3 ligase mutated in neurodegeneration

Diane L. Haakonsen, Michael Heider, Andrew J. Ingersoll, Kayla Vodehnal, Samuel R. Witus, Takeshi Uenaka, Marius Wernig, Michael Rapé
Jan 31 2024
bioRxiv [Preprint] TDP-43 nuclear loss in FTD/ALS causes widespread alternative polyadenylation changes

Yi Zeng, Anastasiia Lovchykova, Tetsuya Akiyama, Chang Liu, Caiwei Guo, Vidhya Maheswari Jawahar, Odilia Sianto, Anna Calliari, Mercedes Prudencio, Dennis W. Dickson, Leonard Petrucelli, Aaron D. Gitler
Jan 22 2024
Nucleic Acids Res. ZEBRA: a hierarchically integrated gene expression atlas of the murine and human brain at single-cell resolution

Flotho M, Amand J, Hirsch P, Grandke F, Wyss-Coray T, Keller A, Kern F.
Jan 5 2024