Publications Research supported by Knight Initiative for Brain Resilience grants and fellowships is advancing our understanding of healthy brain aging and new approaches to combat neurodegenerative disease. Cell Atlas of the aging mouse brain reveals white matter as vulnerable foci Hahn O, Foltz AG, Atkins M, Kedir B, Moran-Losada P, Guldner IH, Munson C, Kern F, Pálovics R, Lu N, Zhang H, Kaur A, Hull J, Huguenard JR, Grönke S, Lehallier B, Partridge L, Keller A, Wyss-Coray T. Sep 14 2023 Nature Aging Platelet factors are induced by longevity factor klotho and enhance cognition in young and aging mice Wyss-Coray T, Park C, Hahn O, Gupta S, et al. Aug 16 2023 bioRxiv APOE4/4 is linked to damaging lipid droplets in Alzheimer's microglia Wyss-Coray T, Abu-Remaileh M, Haney MS, Pálovics R, Munson CN, et al. Jun 25 2023 Nature Medicine Clonal hematopoiesis is associated with protection from Alzheimer’s disease Bouzid H, Belk JA, Jan M, Qi Y, Sarnowski C, Wirth S, Ma L, Chrostek MR, Ahmad H, Nachun D, Yao W; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Beiser A, Bick AG, Bis JC, Fornage M, Longstreth WT Jr, Lopez OL, Natarajan P, Psaty BM, Satizabal CL, Weinstock J, Larson EB, Crane PK, Keene CD, Seshadri S, Satpathy AT, Montine TJ, Jaiswal S. Jun 15 2023 eLife Rapid and precise genome engineering in a naturally short-lived vertebrate Claire N Bedbrook, Ravi D Nath, Rahul Nagvekar, Karl Deisseroth, Anne Brunet May 16 2023
Cell Atlas of the aging mouse brain reveals white matter as vulnerable foci Hahn O, Foltz AG, Atkins M, Kedir B, Moran-Losada P, Guldner IH, Munson C, Kern F, Pálovics R, Lu N, Zhang H, Kaur A, Hull J, Huguenard JR, Grönke S, Lehallier B, Partridge L, Keller A, Wyss-Coray T. Sep 14 2023
Nature Aging Platelet factors are induced by longevity factor klotho and enhance cognition in young and aging mice Wyss-Coray T, Park C, Hahn O, Gupta S, et al. Aug 16 2023
bioRxiv APOE4/4 is linked to damaging lipid droplets in Alzheimer's microglia Wyss-Coray T, Abu-Remaileh M, Haney MS, Pálovics R, Munson CN, et al. Jun 25 2023
Nature Medicine Clonal hematopoiesis is associated with protection from Alzheimer’s disease Bouzid H, Belk JA, Jan M, Qi Y, Sarnowski C, Wirth S, Ma L, Chrostek MR, Ahmad H, Nachun D, Yao W; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Beiser A, Bick AG, Bis JC, Fornage M, Longstreth WT Jr, Lopez OL, Natarajan P, Psaty BM, Satizabal CL, Weinstock J, Larson EB, Crane PK, Keene CD, Seshadri S, Satpathy AT, Montine TJ, Jaiswal S. Jun 15 2023
eLife Rapid and precise genome engineering in a naturally short-lived vertebrate Claire N Bedbrook, Ravi D Nath, Rahul Nagvekar, Karl Deisseroth, Anne Brunet May 16 2023