We’re unlocking the mysteries of lifelong brain resilience Through bold and innovative approaches, we’re decoding how brains stay healthy as we age and driving a future free from dementia. Our Research Featured articles Featured 01 / 06 Knight Initiative - Rosenkranz Aging Symposium Read More Gift advances research into brain resilience and aging Read More New ideas in aging and resilience research launched by Rosenkranz Foundation and Knight Initiative Read More Announcing the 2026 Neurosciences Postdoctoral Scholars Read More Watching a lifetime in motion reveals the architecture of aging Read More Q&A: Probing electrical signals to understand Alzheimer’s disease Read More Our collaborative approach to brain resilience research is unlike any institution in the world. Upcoming EventsJoin us to learn about exciting developments in brain resilience research. Seminar Jan Karlseder - Escape from replicative crisis and immortalization precedes complex genome evolution Oct 26 2026, 12:00 pm – 1:00 pm Seminar Shagayeg Navabpour and Scott Dixon Nov 2 2026, 12:00 pm – 1:00 pm Knight Initiative News View All News Stanford Medicine Digging for clues into the mechanisms of ALS Knight Initiative researcher Aaron Gitler and his team are searching for answers to a major ALS mystery Oct 20 2026 Brain aging Discovery science Molecules and cells Stanford Medicine Biological age versus chronological age: What the science says Knight Initiative Director Tony Wyss-Coray and researchers Anne Brunet and David Rehkopf explain why our body’s age and what’s on your birth certificate aren’t necessarily the same Sep 24 2026 Brain resilience Brain aging Molecules and cells Alzheimer's Association Kyan Younes receives $1 million Alzheimer's Association Part The Cloud grant The grant builds on a Knight Initiative-supported clinical trial of the drug bumetanide for Alzheimer's disease Sep 24 2026 Brain resilience Clinical / translational research Featured Projects Innovation Awards | 2022 Mechanistic dissection and therapeutic capture of an exercise-inducible metabolite signaling pathway for brain resilience Funded Researcher(s) Jonathan Z. Long Thomas Montine, MD, PhD Steven Banik Research Keywords Brain resilience Discovery science Innovation Awards | 2022 Mutant microglia and resilience to Alzheimer’s disease Funded Researcher(s) Siddhartha Jaiswal Marius Wernig Jody Elizabeth Hooper Caleb Lareau Research Keywords Brain resilience Discovery science
New ideas in aging and resilience research launched by Rosenkranz Foundation and Knight Initiative Read More
Seminar Jan Karlseder - Escape from replicative crisis and immortalization precedes complex genome evolution Oct 26 2026, 12:00 pm – 1:00 pm
Stanford Medicine Digging for clues into the mechanisms of ALS Knight Initiative researcher Aaron Gitler and his team are searching for answers to a major ALS mystery Oct 20 2026 Brain aging Discovery science Molecules and cells
Stanford Medicine Biological age versus chronological age: What the science says Knight Initiative Director Tony Wyss-Coray and researchers Anne Brunet and David Rehkopf explain why our body’s age and what’s on your birth certificate aren’t necessarily the same Sep 24 2026 Brain resilience Brain aging Molecules and cells
Alzheimer's Association Kyan Younes receives $1 million Alzheimer's Association Part The Cloud grant The grant builds on a Knight Initiative-supported clinical trial of the drug bumetanide for Alzheimer's disease Sep 24 2026 Brain resilience Clinical / translational research
Innovation Awards | 2022 Mechanistic dissection and therapeutic capture of an exercise-inducible metabolite signaling pathway for brain resilience Funded Researcher(s) Jonathan Z. Long Thomas Montine, MD, PhD Steven Banik Research Keywords Brain resilience Discovery science
Innovation Awards | 2022 Mutant microglia and resilience to Alzheimer’s disease Funded Researcher(s) Siddhartha Jaiswal Marius Wernig Jody Elizabeth Hooper Caleb Lareau Research Keywords Brain resilience Discovery science