We’re unlocking the mysteries of lifelong brain resilience

Through bold and innovative approaches, we’re decoding how brains stay healthy as we age and driving a future free from dementia.

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Our collaborative approach to brain resilience research is unlike any institution in the world.

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Brain Resilience Lab

Our research lab blends the innovation of a startup with the academic rigor and support of Stanford University, driving breakthroughs in healthy brain aging.
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Grants & Training Programs

Uniting scientists across disciplines to catalyze bold advances in the science of neurodegeneration, aging, and resilience.
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Resource Hub

Leveraging advanced tools in sequencing, spatial transcriptomics, and proteomics, we’re building a global library of brain aging datasets, empowering researchers to drive their own studies and advance collective knowledge on brain resilience.
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Brain Omics Central

Offering access to advanced omics technologies, including sequencing, spatial, and proteomics, alongside a growing brain tissue repository.

Upcoming Events
Join us to learn about exciting developments in brain resilience research.

Knight Initiative Events / Seminar Brain Resilience Seminar: Christine Ng and Selin Jessa

Feb 3 2025, 12:00 pm – 1:00 pm
Knight Initiative Events / Symposium Knight Initiative Winter 2025 Symposium

Feb 6 2025, 12:30 pm – 6:00 pm

Researcher profiles Q&A: Unraveling the role of endocannabinoid metabolism in brain aging

Research supported by a Knight Initiative Catalyst Grant explores whether targeting pathways related to the brain’s “chill-out” system could restore youthful resilience and improve cognitive function.
Jan 27 2025

Brain resilience
Research news Blight or Benefit: How Cellular Neighbors Shape the Aging Brain

Researchers at Stanford’s Knight Initiative for Brain Resilience merge spatial transcriptomics and AI to uncover how local cellular interactions drive brain aging and resilience
Dec 19 2024

Brain resilience

Discovery science
Nature Synthetic GPCRs for programmable sensing and control of cell behaviour

Kalogriopoulos NA, Tei R, Yan Y, Klein PM, Ravalin M, Cai B, Soltesz I, Li Y, Ting A.
Dec 4 2024

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